Detalhe da pesquisa
1.
PfCRT mutations conferring piperaquine resistance in falciparum malaria shape the kinetics of quinoline drug binding and transport.
PLoS Pathog
; 19(6): e1011436, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37285379
2.
The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms.
J Biol Chem
; 298(2): 101507, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34929169
3.
Molecular Dynamics Simulations of the Human Ecto-5'-Nucleotidase (h-ecto-5'-NT, CD73): Insights into Protein Flexibility and Binding Site Dynamics.
J Chem Inf Model
; 63(15): 4691-4707, 2023 08 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37532679
4.
Design, synthesis and biological evaluation of antiparasitic dinitroaniline-ether phospholipid hybrids.
Bioorg Chem
; 138: 106615, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37244229
5.
Identification of antiparasitic drug targets using a multi-omics workflow in the acanthocephalan model.
BMC Genomics
; 23(1): 677, 2022 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-36180835
6.
A function of profilin in force generation during malaria parasite motility that is independent of actin binding.
J Cell Sci
; 134(5)2020 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32034083
7.
Global profiling of SRP interaction with nascent polypeptides.
Nature
; 536(7615): 219-23, 2016 08 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27487212
8.
DNA sequence-dependent positioning of the linker histone in a nucleosome: A single-pair FRET study.
Biophys J
; 120(17): 3747-3763, 2021 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34293303
9.
Chromatosome Structure and Dynamics from Molecular Simulations.
Annu Rev Phys Chem
; 71: 101-119, 2020 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32017651
10.
Inter-subunit interactions drive divergent dynamics in mammalian and Plasmodium actin filaments.
PLoS Biol
; 16(7): e2005345, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30011270
11.
Prediction of the Drug-Target Binding Kinetics for Flexible Proteins by Comparative Binding Energy Analysis.
J Chem Inf Model
; 61(7): 3708-3721, 2021 07 26.
Artigo
Inglês
| MEDLINE | ID: mdl-34197096
12.
Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation.
Nature
; 524(7564): 247-51, 2015 Aug 13.
Artigo
Inglês
| MEDLINE | ID: mdl-26245380
13.
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing.
PLoS Pathog
; 14(9): e1007315, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30252911
14.
Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals.
PLoS Comput Biol
; 15(10): e1007382, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31665146
15.
Druggability Assessment in TRAPP Using Machine Learning Approaches.
J Chem Inf Model
; 60(3): 1685-1699, 2020 03 23.
Artigo
Inglês
| MEDLINE | ID: mdl-32105476
16.
A workflow for exploring ligand dissociation from a macromolecule: Efficient random acceleration molecular dynamics simulation and interaction fingerprint analysis of ligand trajectories.
J Chem Phys
; 153(12): 125102, 2020 Sep 28.
Artigo
Inglês
| MEDLINE | ID: mdl-33003755
17.
Influence of Transmembrane Helix Mutations on Cytochrome P450-Membrane Interactions and Function.
Biophys J
; 116(3): 419-432, 2019 02 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30658838
18.
Editorial: The Journal of Molecular Recognition: Changing of the guard.
J Mol Recognit
; 37(3): e3081, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38468426
19.
A unique profilin-actin interface is important for malaria parasite motility.
PLoS Pathog
; 13(5): e1006412, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28552953
20.
KBbox: A Toolbox of Computational Methods for Studying the Kinetics of Molecular Binding.
J Chem Inf Model
; 59(9): 3630-3634, 2019 09 23.
Artigo
Inglês
| MEDLINE | ID: mdl-31381336